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UTILIZTION OF THE SUZUKI COUPLING TO ENHANCE THE ANTITUBERCULOSIS ACTIVITY OF ARYL OXAZOLES

Potent antituberculosis aryl oxazoles can be made in an efficient three step process--formation of β-hydroxy amides with serine benzyl ester; cyclization to afford oxazolines; and then dehydration to give the corresponding oxazoles. Furthermore, incorporation of an appropriate aryl halide allows uti...

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Autors principals: Moraski, Garrett C., Franzblau, Scott G., Miller, Marvin J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192507/
https://ncbi.nlm.nih.gov/pubmed/22003265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3987/COM-09-S(S)69
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