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Scaffold-switching: An exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates

A set of 5,6-fused bicyclic heteroaromatic scaffolds were investigated for their in vitro antitubercular activity versus replicating and non-replicating strains of Mycobacterium tuberculosis (Mtb) in an attempt to find an alternative scaffold to the imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidin...

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Detalhes bibliográficos
Main Authors: Moraski, Garrett C., Oliver, Allen G., Markley, Lowell D., Cho, Sanghyun, Franzblau, Scott G., Miller, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096046/
https://ncbi.nlm.nih.gov/pubmed/24909079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.05.062
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