Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and “Anagrams” Generated Potent Antituberculosis Agents

[Image: see text] Zolpidem (Ambien, 1) is an imidazo[1,2-a]pyridine-3-acetamide and an approved drug for the treatment of insomnia. As medicinal chemists enamored by how structure imparts biological function, we found it to have strikingly similar structure to the antitubercular imidazo[1,2-a]pyridi...

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Detaylı Bibliyografya
Yayımlandı:ACS Infect Dis
Asıl Yazarlar: Moraski, Garrett C., Miller, Patricia A., Bailey, Mai Ann, Ollinger, Juliane, Parish, Tanya, Boshoff, Helena I., Cho, Sanghyun, Anderson, Jeffery R., Mulugeta, Surafel, Franzblau, Scott G., Miller, Marvin J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426345/
https://ncbi.nlm.nih.gov/pubmed/25984566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/id500008t
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