Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions

Por Ashkenazi, Avi
Publicado no J Clin Invest (2015)

To kill a tumor cell: the potential of proapoptotic receptor agonists

Por Ashkenazi, Avi, Herbst, Roy S.
Publicado em 2008

TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8

Por Ikner, Aminah, Ashkenazi, Avi
Publicado em 2011

Fcγ receptors enable anticancer action of proapoptotic and immune-modulatory antibodies

Por Kim, Jeong M., Ashkenazi, Avi
Publicado em 2013

Dynamic mechanical (brush) allodynia in cluster headache: a prevalence study in a tertiary headache clinic

Por Marmura, Michael J., Abbas, Muhammad, Ashkenazi, Avi
Publicado em 2009

Improved identification of allodynic migraine patients using a questionnaire

Por Ashkenazi, Avi, Silberstein, Stephen, Jakubowski, Moshe, Burstein, Rami
Publicado em 2007

Is phonophobia associated with cutaneous allodynia in migraine?

Por Ashkenazi, Avi, Yang, Irene, Mushtaq, Aamir, Oshinsky, Michael L
Publicado em 2010

Long-Term Clinical Outcome of Peripheral Nerve Stimulation for Chronic Headache and Complication Prevention

Por Zhou, Linqiu, Ashkenazi, Avi, Smith, Joseph W, Jen, Na, Deer, Timothy R, Zhou, Chen
Publicado no Anesth Pain Med (2016)

Targeting the Apoptotic Pathway in Chondrosarcoma Using Recombinant Human Apo2L/TRAIL (dulanermin), a Dual Pro-apoptotic Receptor (DR4/DR5) Agonist

Por Subbiah, Vivek, Brown, Robert E, Buryanek, Jamie, Trent, Jonathan, Ashkenazi, Avi, Herbst, Roy, Kurzrock, Razelle
Publicado em 2012

Regulation of Apo2L/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Thyroid Carcinoma Cells

Por Poulaki, Vassiliki, Mitsiades, Constantine S., Kotoula, Vassiliki, Tseleni-Balafouta, Sophia, Ashkenazi, Avi, Koutras, Demetrios A., Mitsiades, Nicholas
Publicado em 2002

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

Por Chen, Tom T., Filvaroff, Ellen, Peng, Jing, Marsters, Scot, Jubb, Adrian, Koeppen, Hartmut, Merchant, Mark, Ashkenazi, Avi
Publicado no EBioMedicine (2015)

Distinct Involvement of the Gab1 and Grb2 Adaptor Proteins in Signal Transduction by the Related Receptor Tyrosine Kinases RON and MET

Por Chaudhuri, Amitabha, Xie, Ming-Hong, Yang, Becky, Mahapatra, Kaushiki, Liu, Jinfeng, Marsters, Scot, Bodepudi, Sweta, Ashkenazi, Avi
Publicado em 2011

FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer

Por Lim, Bora, Scicchitano, Angelique, Beachler, Cheryl, Gusani, Niraj, Sarwani, Nabeel, Yang, Zhaohai, Staveley-O’Carroll, Kevin, Ashkenazi, Avi, Portera, Chia, El-Deiry, Wafik S
Publicado em 2013

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

Por Lu, Min, Lawrence, David A., Marsters, Scot, Acosta-Alvear, Diego, Kimmig, Philipp, Mendez, Aaron S., Paton, Adrienne W., Paton, James C., Walter, Peter, Ashkenazi, Avi
Publicado no Science (2014)

Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages

Por Chaudhuri, Amitabha, Wilson, Nicholas S, Yang, Becky, Paler Martinez, Andres, Liu, Jinfeng, Zhu, Catherine, Bricker, Nicole, Couto, Suzana, Modrusan, Zora, French, Dorothy, Cupp, James, Ashkenazi, Avi
Publicado em 2013

APRIL-Deficient Mice Have Normal Immune System Development

Por Varfolomeev, Eugene, Kischkel, Frank, Martin, Flavius, Seshasayee, Dhaya, Wang, Hua, Lawrence, David, Olsson, Christine, Tom, Lucrece, Erickson, Sharon, French, Dorothy, Schow, Peter, Grewal, Iqbal S., Ashkenazi, Avi
Publicado em 2004

X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists

Por Varfolomeev, Eugene, Alicke, Bruno, Elliott, J. Michael, Zobel, Kerry, West, Kristina, Wong, Harvey, Scheer, Justin M., Ashkenazi, Avi, Gould, Stephen E., Fairbrother, Wayne J., Vucic, Domagoj
Publicado em 2009

Fibroblast Growth Factor Receptor 3 is a Rational Therapeutic Target in Bladder Cancer

Por Gust, Kilian M., McConkey, David J., Awrey, Shannon, Hegarty, Paul K., Qing, Jing, Bondaruk, Jolanta, Ashkenazi, Avi, Czerniak, Bogdan, Dinney, Colin P., Black, Peter C.
Publicado em 2013

Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display

Por Nair, Pradeep M., Flores, Heather, Gogineni, Alvin, Marsters, Scot, Lawrence, David A., Kelley, Robert F., Ngu, Hai, Sagolla, Meredith, Komuves, Laszlo, Bourgon, Richard, Settleman, Jeffrey, Ashkenazi, Avi
Publicado no Proc Natl Acad Sci U S A (2015)

Death-receptor activation halts clathrin-dependent endocytosis

Por Austin, Cary D., Lawrence, David A., Peden, Andrew A., Varfolomeev, Eugene E., Totpal, Klara, De Mazière, Ann M., Klumperman, Judith, Arnott, David, Pham, Victoria, Scheller, Richard H., Ashkenazi, Avi
Publicado em 2006