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Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages
Toll-like receptors (TLRs) enable metazoans to mount effective innate immune responses to microbial and viral pathogens, as well as to endogenous host-derived ligands. It is understood that genetic background of the host can influence TLR responsiveness, altering susceptibility to pathogen infection...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736205/ https://ncbi.nlm.nih.gov/pubmed/23817579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.27 |
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