Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages

Toll-like receptors (TLRs) enable metazoans to mount effective innate immune responses to microbial and viral pathogens, as well as to endogenous host-derived ligands. It is understood that genetic background of the host can influence TLR responsiveness, altering susceptibility to pathogen infection...

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Hlavní autoři: Chaudhuri, Amitabha, Wilson, Nicholas S, Yang, Becky, Paler Martinez, Andres, Liu, Jinfeng, Zhu, Catherine, Bricker, Nicole, Couto, Suzana, Modrusan, Zora, French, Dorothy, Cupp, James, Ashkenazi, Avi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736205/
https://ncbi.nlm.nih.gov/pubmed/23817579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.27
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