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Substrate Stiffness Regulates Proinflammatory Mediator Production through TLR4 Activity in Macrophages

Clinical data show that disease adversely affects tissue elasticity or stiffness. While macrophage activity plays a critical role in driving disease pathology, there are limited data available on the effects of tissue stiffness on macrophage activity. In this study, the effects of substrate stiffnes...

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Vydáno v:PLoS One
Hlavní autoři: Previtera, Michelle L., Sengupta, Amitabha
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692401/
https://ncbi.nlm.nih.gov/pubmed/26710072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145813
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