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Apolipoprotein E Inhibits Toll-like Receptor (TLR)-3 and TLR-4 Mediated Macrophage Activation through Distinct Mechanisms

Previous studies showed that apolipoprotein E (apoE) expression in macrophages suppresses inflammatory response. Whether the endogenously synthesized apoE acts intracellularly or after its secretion in suppressing macrophage inflammation remains unclear. The current study used the murine macrophage...

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Detalhes bibliográficos
Main Authors: ZHU, Yanjuan, KODVAWALA, Ahmer, HUI, David Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050041/
https://ncbi.nlm.nih.gov/pubmed/20218969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100016
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