Glycolytic reprogramming of macrophages activated by NOD1 and TLR4 agonists: No association with proinflammatory cytokine production in normoxia

Upon activation with pathogen-associated molecular patterns, metabolism of macrophages and dendritic cells is shifted from oxidative phosphorylation to aerobic glycolysis, which is considered important for proinflammatory cytokine production. Fragments of bacterial peptidoglycan (muramyl peptides) a...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Murugina, Nina E., Budikhina, Anna S., Dagil, Yulia A., Maximchik, Polina V., Balyasova, Lyudmila S., Murugin, Vladimir V., Melnikov, Mikhail V., Sharova, Viktoriya S., Nikolaeva, Anna M., Chkadua, Georgy Z., Pinegin, Boris V., Pashenkov, Mikhail V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062164/
https://ncbi.nlm.nih.gov/pubmed/32005665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010589
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