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To kill a tumor cell: the potential of proapoptotic receptor agonists

Disturbances in mechanisms that direct abnormal cells to undergo apoptosis frequently and critically contribute to tumorigenesis, yielding a logical target for potential therapeutic intervention. There is currently heightened interest in the extrinsic apoptosis pathway, with several proapoptotic rec...

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Detalhes bibliográficos
Main Authors: Ashkenazi, Avi, Herbst, Roy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396896/
https://ncbi.nlm.nih.gov/pubmed/18523647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34359
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