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To kill a tumor cell: the potential of proapoptotic receptor agonists

Disturbances in mechanisms that direct abnormal cells to undergo apoptosis frequently and critically contribute to tumorigenesis, yielding a logical target for potential therapeutic intervention. There is currently heightened interest in the extrinsic apoptosis pathway, with several proapoptotic rec...

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Autors principals: Ashkenazi, Avi, Herbst, Roy S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396896/
https://ncbi.nlm.nih.gov/pubmed/18523647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34359
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