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Fcγ receptors enable anticancer action of proapoptotic and immune-modulatory antibodies

Antibodies have important roles in controlling cellular immunity through interaction with activating or inhibitory Fcγ receptors (FcγRs). FcγR engagement can facilitate receptor cross-linking on target cells, or induce retrograde FcγR signals to stimulate or suppress antibody-dependent, cell-mediate...

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Bibliografiske detaljer
Main Authors: Kim, Jeong M., Ashkenazi, Avi
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754862/
https://ncbi.nlm.nih.gov/pubmed/23980122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131625
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