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C5a receptor enables participation of mast cells in immune complex arthritis independent of Fc γ receptor modulation
OBJECTIVE: Mast cells are tissue-resident immune sentinels implicated in the pathogenesis of inflammatory joint disease. We hypothesized that complement fragments could be key activators of synovial mast cells in autoimmune arthritis. METHODS: In vivo studies employed murine K/BxN arthritis, a dista...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970731/ https://ncbi.nlm.nih.gov/pubmed/20662064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27659 |
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