The structure of interleukin-33 and its interaction with the ST2 and IL-1RAcP receptors – insight into the arrangement of heterotrimeric interleukin-1 signaling complexes

Members of the interleukin-1 (IL-1) family of cytokines play major roles in host defense and immune system regulation in infectious and inflammatory diseases. IL-1 cytokines trigger a biological response in effector cells by assembling a heterotrimeric signaling complex with two IL-1 receptor chains...

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Detalhes bibliográficos
Main Authors: Lingel, Andreas, Weiss, Thomas M., Niebuhr, Marc, Pan, Borlan, Appleton, Brent A., Wiesmann, Christian, Bazan, J. Fernando, Fairbrother, Wayne J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766095/
https://ncbi.nlm.nih.gov/pubmed/19836339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.08.009
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