Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)

The cytokine interleukin 1(IL-1) initiates a wide range of proinflammatory cascades and its inhibition has been shown to decrease inflammation in a variety of diseases. IL-1 receptor accessory protein (IL-1RAcP) is an indispensible part of the IL-1R complex that stabilizes IL-1/IL-1R interaction and...

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Detalhes bibliográficos
Main Authors: Yılmaz-Eliş, A Seda, Aartsma-Rus, Annemieke, ‘t Hoen, Peter AC, Safdar, Huma, Breukel, Cor, van Vlijmen, Bart JM, van Deutekom, Judith, de Kimpe, Sjef, van Ommen, Gert-Jan, Verbeek, J Sjef
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564974/
https://ncbi.nlm.nih.gov/pubmed/23340324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.58
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