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Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy

BACKGROUND: Antisense-mediated exon skipping is currently one of the most promising therapeutic approaches for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs) targeting specific exons the DMD reading frame is restored and partially functional dystrophins are produced. Foll...

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Detalhes bibliográficos
Main Authors: Aartsma-Rus, Annemieke, Janson, Anneke AM, van Ommen, Gert-Jan B, van Deutekom, Judith CT
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931584/
https://ncbi.nlm.nih.gov/pubmed/17612397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-43
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