Assessment of the feasibility of exon 45–55 multiexon skipping for duchenne muscular dystrophy

BACKGROUND: The specific skipping of an exon, induced by antisense oligonucleotides (AON) during splicing, has shown to be a promising therapeutic approach for Duchenne muscular dystrophy (DMD) patients. As different mutations require skipping of different exons, this approach is mutation dependent....

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Hlavní autoři: van Vliet, Laura, de Winter, Christa L, van Deutekom, Judith CT, van Ommen, Gert-Jan B, Aartsma-Rus, Annemieke
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2611974/
https://ncbi.nlm.nih.gov/pubmed/19046429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-105
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