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Antisense-mediated exon skipping: A versatile tool with therapeutic and research applications

Antisense-mediated modulation of splicing is one of the few fields where antisense oligonucleotides (AONs) have been able to live up to their expectations. In this approach, AONs are implemented to restore cryptic splicing, to change levels of alternatively spliced genes, or, in case of Duchenne mus...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aartsma-Rus, Annemieke, van Ommen, Gert-Jan B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986821/
https://ncbi.nlm.nih.gov/pubmed/17684229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.653607
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