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Progress in therapeutic antisense applications for neuromuscular disorders

Neuromuscular disorders are a frequent cause of chronic disability in man. They often result from mutations in single genes and are thus, in principle, well suited for gene therapy. However, the tissues involved (muscle and the central nervous system) are post-mitotic, which poses a challenge for mo...

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Podrobná bibliografie
Hlavní autoři: Aartsma-Rus, Annemieke, van Ommen, Gert-Jan B
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987179/
https://ncbi.nlm.nih.gov/pubmed/19809477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.160
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