Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis

Defects in apoptosis contribute to treatment resistance and poor outcome of pancreatic cancer, calling for novel therapeutic strategies. Here, we provide the first evidence that nuclear factor (NF) κB is required for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-i...

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Главные авторы: Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press Inc. 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257191/
https://ncbi.nlm.nih.gov/pubmed/22241962
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