Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis

Defects in apoptosis contribute to treatment resistance and poor outcome of pancreatic cancer, calling for novel therapeutic strategies. Here, we provide the first evidence that nuclear factor (NF) κB is required for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-i...

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Bibliografische gegevens
Hoofdauteurs: Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press Inc. 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257191/
https://ncbi.nlm.nih.gov/pubmed/22241962
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