Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells

We explored the potential of Smac mimetics, which antagonize Inhibitor of Apoptosis (IAP) proteins, for chemosensitization of neuroblastoma (NB). Here, we report that Smac mimetics, e.g. BV6, prime NB cells for chemotherapeutics including the topoisomerase II inhibitor doxorubicin (DOX) and vinca al...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Czaplinski, Sebastian, Abhari, Behnaz Ahangarian, Torkov, Alica, SeggewiΔ, Dominik, Hugle, Manuela, Fulda, Simone
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research paper: Autophagy and Cell Death
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747171/
https://ncbi.nlm.nih.gov/pubmed/26575016
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