Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells

We explored the potential of Smac mimetics, which antagonize Inhibitor of Apoptosis (IAP) proteins, for chemosensitization of neuroblastoma (NB). Here, we report that Smac mimetics, e.g. BV6, prime NB cells for chemotherapeutics including the topoisomerase II inhibitor doxorubicin (DOX) and vinca al...

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Pubblicato in:Oncotarget
Autori principali: Czaplinski, Sebastian, Abhari, Behnaz Ahangarian, Torkov, Alica, SeggewiΔ, Dominik, Hugle, Manuela, Fulda, Simone
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research paper: Autophagy and Cell Death
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747171/
https://ncbi.nlm.nih.gov/pubmed/26575016
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