Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells

We explored the potential of Smac mimetics, which antagonize Inhibitor of Apoptosis (IAP) proteins, for chemosensitization of neuroblastoma (NB). Here, we report that Smac mimetics, e.g. BV6, prime NB cells for chemotherapeutics including the topoisomerase II inhibitor doxorubicin (DOX) and vinca al...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Czaplinski, Sebastian, Abhari, Behnaz Ahangarian, Torkov, Alica, SeggewiΔ, Dominik, Hugle, Manuela, Fulda, Simone
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research paper: Autophagy and Cell Death
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747171/
https://ncbi.nlm.nih.gov/pubmed/26575016
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