Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

Since Inhibitor of Apoptosis (IAP) proteins have been implicated in cellular adaptation to endoplasmic reticulum (ER) stress, we investigated the regulation of ER stress-induced apoptosis by small-molecule second mitochondria-derived activator of caspase (Smac) mimetics that antagonize IAP proteins....

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Vydáno v:Cell Death Dis
Hlavní autoři: Abhari, Behnaz Ahangarian, McCarthy, Nicole, Le Berre, Marie, Kilcoyne, Michelle, Joshi, Lokesh, Agostinis, Patrizia, Fulda, Simone
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377606/
https://ncbi.nlm.nih.gov/pubmed/30770792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1381-z
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