Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

Since Inhibitor of Apoptosis (IAP) proteins have been implicated in cellular adaptation to endoplasmic reticulum (ER) stress, we investigated the regulation of ER stress-induced apoptosis by small-molecule second mitochondria-derived activator of caspase (Smac) mimetics that antagonize IAP proteins....

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Abhari, Behnaz Ahangarian, McCarthy, Nicole, Le Berre, Marie, Kilcoyne, Michelle, Joshi, Lokesh, Agostinis, Patrizia, Fulda, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377606/
https://ncbi.nlm.nih.gov/pubmed/30770792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1381-z
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