Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis

Defects in apoptosis contribute to treatment resistance and poor outcome of pancreatic cancer, calling for novel therapeutic strategies. Here, we provide the first evidence that nuclear factor (NF) κB is required for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-i...

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Main Authors: Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Formáid: Artigo
Teanga:Inglês
Foilsithe: Neoplasia Press Inc. 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257191/
https://ncbi.nlm.nih.gov/pubmed/22241962
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