Non-inhibited miRNAs shape the cellular response to anti-miR

по Androsavich, John R., Chau, B. Nelson
Опубликовано 2014

Separation of Anti-Proliferation and Anti-Apoptotic Functions of Retinoblastoma Protein through Targeted Mutations of Its A/B Domain

по Chau, B. Nelson, Pan, Chris W., Wang, Jean Y.J.
Опубликовано 2006

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

по Androsavich, John R., Chau, B. Nelson, Bhat, Balkrishen, Linsley, Peter S., Walter, Nils G.
Опубликовано 2012

Survival motor neuron protein modulates neuron-specific apoptosis

по Kerr, Douglas A., Nery, Jocelyn P., Traystman, Richard J., Chau, B. Nelson, Hardwick, J. Marie
Опубликовано 2000

Antiapoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-Mediated Conversion to Proapoptotic Proteins

по Bellows, David S., Chau, B. Nelson, Lee, Percy, Lazebnik, Yuri, Burns, William H., Hardwick, J. Marie
Опубликовано 2000

Tumor Necrosis Factor Alpha-Induced Apoptosis Requires p73 and c-ABL Activation Downstream of RB Degradation

по Chau, B. Nelson, Chen, Tung-Ti, Wan, Yisong Y., DeGregori, James, Wang, Jean Y. J.
Опубликовано 2004

Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity

по Jackson, Aimee L., Burchard, Julja, Schelter, Janell, Chau, B. Nelson, Cleary, Michele, Lim, Lee, Linsley, Peter S.
Опубликовано 2006

Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

по Hogan, Daniel J., Vincent, Thomas M., Fish, Sarah, Marcusson, Eric G., Bhat, Balkrishen, Chau, B. Nelson, Zisoulis, Dimitrios G.
Опубликовано 2014

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

по Koval, Erica D., Shaner, Carey, Zhang, Peter, du Maine, Xavier, Fischer, Kimberlee, Tay, Jia, Chau, B. Nelson, Wu, Gregory F., Miller, Timothy M.
Опубликовано 2013

Polysome shift assay for direct measurement of miRNA inhibition by anti-miRNA drugs

по Androsavich, John R., Sobczynski, Daniel J., Liu, Xueqing, Pandya, Shweta, Kaimal, Vivek, Owen, Tate, Liu, Kai, MacKenna, Deidre A., Chau, B. Nelson
Опубликовано в: Nucleic Acids Res (2016)

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

по Bertero, Thomas, Cottrill, Katherine, Krauszman, Adrienn, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Waxman, Aaron B., Chau, B. Nelson, Kuebler, Wolfgang M., Chan, Stephen Y.
Опубликовано в: J Biol Chem (2015)

Functional genomics identifies therapeutic targets for MYC-driven cancer

по Toyoshima, Masafumi, Howie, Heather L., Imakura, Maki, Walsh, Ryan M., Annis, James E., Chang, Aaron N., Frazier, Jason, Chau, B. Nelson, Loboda, Andrey, Linsley, Peter S., Cleary, Michele A., Park, Julie R., Grandori, Carla
Опубликовано 2012

Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy

по Woo, Caroline J., Maier, Verena K., Davey, Roshni, Brennan, James, Li, Guangde, Brothers, John, Schwartz, Brian, Gordo, Susana, Kasper, Anne, Okamoto, Trevor R., Johansson, Hans E., Mandefro, Berhan, Sareen, Dhruv, Bialek, Peter, Chau, B. Nelson, Bhat, Balkrishen, Bullough, David, Barsoum, James
Опубликовано в: Proc Natl Acad Sci U S A (2017)

Aven-dependent activation of ATM following DNA damage

по Guo, Jessie Yanxiang, Yamada, Ayumi, Kajino, Taisuke, Wu, Judy Qiju, Tang, Wanli, Freel, Christopher D., Feng, Junjie, Chau, B. Nelson, Wang, Michael Zhuo, Margolis, Seth, Yoo, Hae Yong, Wang, Xiao-Fan, Dunphy, William G., Irusta, Pablo M., Hardwick, J. Marie, Kornbluth, Sally
Опубликовано 2008

MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways

по Chau, B. Nelson, Xin, Cuiyan, Hartner, Jochen, Ren, Shuyu, Castano, Ana P., Linn, Geoffrey, Li, Jian, Tran, Phong T, Kaimal, Vivek, Huang, Xinqiang, Chang, Aaron N, Li, Shenyan, Kalra, Aarti, Grafals, Monica, Portilla, Didier, MacKenna, Deidre A., Orkin, Stuart H., Duffield, Jeremy S.
Опубликовано 2012

Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways

по Gomez, Ivan G., MacKenna, Deidre A., Johnson, Bryce G., Kaimal, Vivek, Roach, Allie M., Ren, Shuyu, Nakagawa, Naoki, Xin, Cuiyan, Newitt, Rick, Pandya, Shweta, Xia, Tai-He, Liu, Xueqing, Borza, Dorin-Bogdan, Grafals, Monica, Shankland, Stuart J., Himmelfarb, Jonathan, Portilla, Didier, Liu, Shiguang, Chau, B. Nelson, Duffield, Jeremy S.
Опубликовано в: J Clin Invest (2014)

Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

по Dubinsky, Amy N., Dastidar, Somasish Ghosh, Hsu, Cynthia L., Zahra, Rabaab, Djakovic, Stevan, Duarte, Sonia, Esau, Christine C., Spencer, Brian, Ashe, Travis D., Fischer, Kimberlee M., MacKenna, Deidre A., Sopher, Bryce L., Masliah, Eliezer, Gaasterland, Terry, Chau, B. Nelson, de Almeida, Luis Pereira, Morrison, Bradley E., La Spada, Albert R.
Опубликовано в: Cell Metab (2014)

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

по Bertero, Thomas, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Vargas, Sara O., Graham, Brian B., Kumar, Rahul, Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., West, James D., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Cottrill, Katherine A., Chan, Stephen Y.
Опубликовано 2014

Matrix remodeling promotes pulmonary hypertension through feedback mechanoactivation of the YAP/TAZ-miR-130/301 circuit

по Bertero, Thomas, Cottrill, Katherine A., Lu, Yu, Haeger, Christina M., Dieffenbach, Paul, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Kaimal, Vivek, Zhang, Ying-Yi, Graham, Brian B., Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., Vargas, Sara O., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Fredenburgh, Laura E., Chan, Stephen Y.
Опубликовано в: Cell Rep (2015)

Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

по White, Kevin, Lu, Yu, Annis, Sofia, Hale, Andrew E, Chau, B Nelson, Dahlman, James E, Hemann, Craig, Opotowsky, Alexander R, Vargas, Sara O, Rosas, Ivan, Perrella, Mark A, Osorio, Juan C, Haley, Kathleen J, Graham, Brian B, Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W Dean, Ross, David J, Khan, Omar F, Bader, Andrew, Gochuico, Bernadette R, Matar, Majed, Polach, Kevin, Johannessen, Nicolai M, Prosser, Haydn M, Anderson, Daniel G, Langer, Robert, Zweier, Jay L, Bindoff, Laurence A, Systrom, David, Waxman, Aaron B, Jin, Richard C, Chan, Stephen Y
Опубликовано в: EMBO Mol Med (2015)