Non-inhibited miRNAs shape the cellular response to anti-miR

Por Androsavich, John R., Chau, B. Nelson
Publicado em 2014

Separation of Anti-Proliferation and Anti-Apoptotic Functions of Retinoblastoma Protein through Targeted Mutations of Its A/B Domain

Por Chau, B. Nelson, Pan, Chris W., Wang, Jean Y.J.
Publicado em 2006

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

Por Androsavich, John R., Chau, B. Nelson, Bhat, Balkrishen, Linsley, Peter S., Walter, Nils G.
Publicado em 2012

Survival motor neuron protein modulates neuron-specific apoptosis

Por Kerr, Douglas A., Nery, Jocelyn P., Traystman, Richard J., Chau, B. Nelson, Hardwick, J. Marie
Publicado em 2000

Antiapoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-Mediated Conversion to Proapoptotic Proteins

Por Bellows, David S., Chau, B. Nelson, Lee, Percy, Lazebnik, Yuri, Burns, William H., Hardwick, J. Marie
Publicado em 2000

Tumor Necrosis Factor Alpha-Induced Apoptosis Requires p73 and c-ABL Activation Downstream of RB Degradation

Por Chau, B. Nelson, Chen, Tung-Ti, Wan, Yisong Y., DeGregori, James, Wang, Jean Y. J.
Publicado em 2004

Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity

Por Jackson, Aimee L., Burchard, Julja, Schelter, Janell, Chau, B. Nelson, Cleary, Michele, Lim, Lee, Linsley, Peter S.
Publicado em 2006

Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

Por Hogan, Daniel J., Vincent, Thomas M., Fish, Sarah, Marcusson, Eric G., Bhat, Balkrishen, Chau, B. Nelson, Zisoulis, Dimitrios G.
Publicado em 2014

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

Por Koval, Erica D., Shaner, Carey, Zhang, Peter, du Maine, Xavier, Fischer, Kimberlee, Tay, Jia, Chau, B. Nelson, Wu, Gregory F., Miller, Timothy M.
Publicado em 2013

Polysome shift assay for direct measurement of miRNA inhibition by anti-miRNA drugs

Por Androsavich, John R., Sobczynski, Daniel J., Liu, Xueqing, Pandya, Shweta, Kaimal, Vivek, Owen, Tate, Liu, Kai, MacKenna, Deidre A., Chau, B. Nelson
Publicado no Nucleic Acids Res (2016)

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

Por Bertero, Thomas, Cottrill, Katherine, Krauszman, Adrienn, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Waxman, Aaron B., Chau, B. Nelson, Kuebler, Wolfgang M., Chan, Stephen Y.
Publicado no J Biol Chem (2015)

Functional genomics identifies therapeutic targets for MYC-driven cancer

Por Toyoshima, Masafumi, Howie, Heather L., Imakura, Maki, Walsh, Ryan M., Annis, James E., Chang, Aaron N., Frazier, Jason, Chau, B. Nelson, Loboda, Andrey, Linsley, Peter S., Cleary, Michele A., Park, Julie R., Grandori, Carla
Publicado em 2012

Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy

Por Woo, Caroline J., Maier, Verena K., Davey, Roshni, Brennan, James, Li, Guangde, Brothers, John, Schwartz, Brian, Gordo, Susana, Kasper, Anne, Okamoto, Trevor R., Johansson, Hans E., Mandefro, Berhan, Sareen, Dhruv, Bialek, Peter, Chau, B. Nelson, Bhat, Balkrishen, Bullough, David, Barsoum, James
Publicado no Proc Natl Acad Sci U S A (2017)

Aven-dependent activation of ATM following DNA damage

Por Guo, Jessie Yanxiang, Yamada, Ayumi, Kajino, Taisuke, Wu, Judy Qiju, Tang, Wanli, Freel, Christopher D., Feng, Junjie, Chau, B. Nelson, Wang, Michael Zhuo, Margolis, Seth, Yoo, Hae Yong, Wang, Xiao-Fan, Dunphy, William G., Irusta, Pablo M., Hardwick, J. Marie, Kornbluth, Sally
Publicado em 2008

MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways

Por Chau, B. Nelson, Xin, Cuiyan, Hartner, Jochen, Ren, Shuyu, Castano, Ana P., Linn, Geoffrey, Li, Jian, Tran, Phong T, Kaimal, Vivek, Huang, Xinqiang, Chang, Aaron N, Li, Shenyan, Kalra, Aarti, Grafals, Monica, Portilla, Didier, MacKenna, Deidre A., Orkin, Stuart H., Duffield, Jeremy S.
Publicado em 2012

Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways

Por Gomez, Ivan G., MacKenna, Deidre A., Johnson, Bryce G., Kaimal, Vivek, Roach, Allie M., Ren, Shuyu, Nakagawa, Naoki, Xin, Cuiyan, Newitt, Rick, Pandya, Shweta, Xia, Tai-He, Liu, Xueqing, Borza, Dorin-Bogdan, Grafals, Monica, Shankland, Stuart J., Himmelfarb, Jonathan, Portilla, Didier, Liu, Shiguang, Chau, B. Nelson, Duffield, Jeremy S.
Publicado no J Clin Invest (2014)

Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

Por Dubinsky, Amy N., Dastidar, Somasish Ghosh, Hsu, Cynthia L., Zahra, Rabaab, Djakovic, Stevan, Duarte, Sonia, Esau, Christine C., Spencer, Brian, Ashe, Travis D., Fischer, Kimberlee M., MacKenna, Deidre A., Sopher, Bryce L., Masliah, Eliezer, Gaasterland, Terry, Chau, B. Nelson, de Almeida, Luis Pereira, Morrison, Bradley E., La Spada, Albert R.
Publicado no Cell Metab (2014)

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

Por Bertero, Thomas, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Vargas, Sara O., Graham, Brian B., Kumar, Rahul, Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., West, James D., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Cottrill, Katherine A., Chan, Stephen Y.
Publicado em 2014

Matrix remodeling promotes pulmonary hypertension through feedback mechanoactivation of the YAP/TAZ-miR-130/301 circuit

Por Bertero, Thomas, Cottrill, Katherine A., Lu, Yu, Haeger, Christina M., Dieffenbach, Paul, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Kaimal, Vivek, Zhang, Ying-Yi, Graham, Brian B., Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., Vargas, Sara O., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Fredenburgh, Laura E., Chan, Stephen Y.
Publicado no Cell Rep (2015)

Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

Por White, Kevin, Lu, Yu, Annis, Sofia, Hale, Andrew E, Chau, B Nelson, Dahlman, James E, Hemann, Craig, Opotowsky, Alexander R, Vargas, Sara O, Rosas, Ivan, Perrella, Mark A, Osorio, Juan C, Haley, Kathleen J, Graham, Brian B, Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W Dean, Ross, David J, Khan, Omar F, Bader, Andrew, Gochuico, Bernadette R, Matar, Majed, Polach, Kevin, Johannessen, Nicolai M, Prosser, Haydn M, Anderson, Daniel G, Langer, Robert, Zweier, Jay L, Bindoff, Laurence A, Systrom, David, Waxman, Aaron B, Jin, Richard C, Chan, Stephen Y
Publicado no EMBO Mol Med (2015)