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Survival motor neuron protein modulates neuron-specific apoptosis

Spinal muscular atrophy (SMA) is attributed to mutations in the SMN1 gene, leading to loss of spinal cord motor neurons. The neurotropic Sindbis virus vector system was used to investigate a role for the survival motor neuron (SMN) protein in regulating neuronal apoptosis. Here we show that SMN prot...

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Detalhes bibliográficos
Main Authors: Kerr, Douglas A., Nery, Jocelyn P., Traystman, Richard J., Chau, B. Nelson, Hardwick, J. Marie
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27221/
https://ncbi.nlm.nih.gov/pubmed/11078511
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