Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

microRNAs (miRNAs) are dysregulated in a variety of disease states, suggesting that this newly discovered class of gene expression repressors may be viable therapeutic targets. A microarray of miRNA changes in ALS-model superoxide dismutase 1 (SOD1)(G93A) rodents identified 12 miRNAs as significantl...

Full description

Saved in:
Bibliographic Details
Main Authors: Koval, Erica D., Shaner, Carey, Zhang, Peter, du Maine, Xavier, Fischer, Kimberlee, Tay, Jia, Chau, B. Nelson, Wu, Gregory F., Miller, Timothy M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781640/
https://ncbi.nlm.nih.gov/pubmed/23740943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt261
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items