Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease

Por Dahlman, James E., Abudayyeh, Omar O., Joung, Julia, Gootenberg, Jonathan S., Zhang, Feng, Konermann, Silvana
Publicado no Nat Biotechnol (2015)

Alkane-modified short polyethyleneimine for siRNA delivery

Por Schroeder, Avi, Dahlman, James E., Sahay, Gaurav, Love, Kevin T., Jiang, Shan, Eltoukhy, Ahmed A., Levins, Christopher G., Wang, Yingxia, Anderson, Daniel G.
Publicado em 2011

Interaction between integrin α(5) and PDE4D regulates endothelial inflammatory signalling

Por Yun, Sanguk, Budatha, Madhusudhan, Dahlman, James E., Coon, Brian G., Cameron, Ryan T., Langer, Robert, Anderson, Daniel G., Baillie, George, Schwartz, Martin A.
Publicado no Nat Cell Biol (2016)

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Por Dahlman, James E., Kauffman, Kevin J., Xing, Yiping, Shaw, Taylor E., Mir, Faryal F., Dlott, Chloe C., Langer, Robert, Anderson, Daniel G., Wang, Eric T.
Publicado no Proc Natl Acad Sci U S A (2017)

Ionizable amphiphilic dendrimer-based nanomaterials with alkyl chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo

Por Khan, Omar F., Zaia, Edmond W., Yin, Hao, Bogorad, Roman L., Pelet, Jeisa M., Webber, Matthew J., Zhuang, Iris, Dahlman, James E., Langer, Robert, Anderson, Daniel G.
Publicado no Angew Chem Int Ed Engl (2014)

Macrophage Notch ligand Delta-like 4 promotes vein graft lesion development: implications for the treatment of vein graft failure

Por Koga, Jun-ichiro, Nakano, Toshiaki, Dahlman, James E., Figueiredo, Jose-Luiz, Zhang, Hengmin, Decano, Julius, Khan, Omar F, Niida, Tomiharu, Iwata, Hiroshi, Aster, Jon C., Yagita, Hideo, Anderson, Daniel G., Ozaki, C. Keith, Aikawa, Masanori
Publicado no Arterioscler Thromb Vasc Biol (2015)

Small RNA combination therapy for lung cancer

Por Xue, Wen, Dahlman, James E., Tammela, Tuomas, Khan, Omar F., Sood, Sabina, Dave, Apeksha, Cai, Wenxin, Chirino, Leilani M., Yang, Gillian R., Bronson, Roderick, Crowley, Denise G., Sahay, Gaurav, Schroeder, Avi, Langer, Robert, Anderson, Daniel G., Jacks, Tyler
Publicado em 2014

Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Por Khan, Omar F., Zaia, Edmond W., Jhunjhunwala, Siddharth, Xue, Wen, Cai, Wenxin, Yun, Dong Soo, Barnes, Carmen M., Dahlman, James E., Dong, Yizhou, Pelet, Jeisa M., Webber, Matthew J., Tsosie, Jonathan K., Jacks, Tyler E., Langer, Robert, Anderson, Daniel G.
Publicado no Nano Lett (2015)

Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure

Por Sager, Hendrik B., Hulsmans, Maarten, Lavine, Kory J., Moreira, Marina B., Heidt, Timo, Courties, Gabriel, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F., Dahlman, James E., Borodovsky, Anna, Fitzgerald, Kevin, Anderson, Daniel G., Weissleder, Ralph, Libby, Peter, Swirski, Filip K., Nahrendorf, Matthias
Publicado no Circ Res (2016)

Loss of α-catenin elicits a cholestatic response and impairs liver regeneration

Por Herr, Keira Joann, Tsang, Ying-hung Nicole, Ong, Joanne Wei En, Li, Qiushi, Yap, Lai Lai, Yu, Weimiao, Yin, Hao, Bogorad, Roman L., Dahlman, James E., Chan, Yee Gek, Bay, Boon Huat, Singaraja, Roshni, Anderson, Daniel G., Koteliansky, Victor, Viasnoff, Virgile, Thiery, Jean Paul
Publicado em 2014

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

Por Platt, Randall J., Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Xavier, Ramnik J., Langer, Robert, Anderson, Daniel G., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng
Publicado no Cell (2014)

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction

Por Sager, Hendrik B., Dutta, Partha, Dahlman, James E., Hulsmans, Maarten, Courties, Gabriel, Sun, Yuan, Heidt, Timo, Vinegoni, Claudio, Borodovsky, Anna, Fitzgerald, Kevin, Wojtkiewicz, Gregory R., Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F., Kauffman, Kevin J., Xing, Yiping, Shaw, Taylor E., Libby, Peter, Langer, Robert, Weissleder, Ralph, Swirski, Filip K., Anderson, Daniel G., Nahrendorf, Matthias
Publicado no Sci Transl Med (2016)

Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

Por White, Kevin, Lu, Yu, Annis, Sofia, Hale, Andrew E, Chau, B Nelson, Dahlman, James E, Hemann, Craig, Opotowsky, Alexander R, Vargas, Sara O, Rosas, Ivan, Perrella, Mark A, Osorio, Juan C, Haley, Kathleen J, Graham, Brian B, Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W Dean, Ross, David J, Khan, Omar F, Bader, Andrew, Gochuico, Bernadette R, Matar, Majed, Polach, Kevin, Johannessen, Nicolai M, Prosser, Haydn M, Anderson, Daniel G, Langer, Robert, Zweier, Jay L, Bindoff, Laurence A, Systrom, David, Waxman, Aaron B, Jin, Richard C, Chan, Stephen Y
Publicado no EMBO Mol Med (2015)

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

Por Dahlman, James E., Barnes, Carmen, Khan, Omar, Thiriot, Aude, Jhunjunwala, Siddharth, Shaw, Taylor E., Xing, Yiping, Sager, Hendrik B., Sahay, Gaurav, Speciner, Lauren, Bader, Andrew, Bogorad, Roman L., Yin, Hao, Racie, Tim, Dong, Yizhou, Jiang, Shan, Seedorf, Danielle, Dave, Apeksha, Sandu, Kamaljeet S., Webber, Matthew J., Novobrantseva, Tatiana, Ruda, Vera M., Lytton-Jean, Abigail K.R., Levins, Christopher G., Kalish, Brian, Mudge, Dayna K., Perez, Mario, Abezgauz, Ludmila, Dutta, Partha, Smith, Lynelle, Charisse, Klaus, Kieran, Mark W., Fitzgerald, Kevin, Nahrendorf, Matthias, Danino, Dganit, Tuder, Rubin M., von Andrian, Ulrich H., Akinc, Akin, Schroeder, Avi, Panigrahy, Dipak, Kotelianski, Victor, Langer, Robert, Anderson, Daniel G.
Publicado em 2014