Orthogonal gene knock out and activation with a catalytically active Cas9 nuclease

nork Dahlman, James E., Abudayyeh, Omar O., Joung, Julia, Gootenberg, Jonathan S., Zhang, Feng, Konermann, Silvana
Argitaratua izan da Nat Biotechnol (2015)

Transcriptome engineering with RNA-targeting Type VI-D CRISPR effectors

nork Konermann, Silvana, Lotfy, Peter, Brideau, Nicholas J., Oki, Jennifer, Shokhirev, Maxim N., Hsu, Patrick D.
Argitaratua izan da Cell (2018)

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

nork Nishimasu, Hiroshi, Ran, F. Ann, Hsu, Patrick D., Konermann, Silvana, Shehata, Soraya, Dohmae, Naoshi, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu
Argitaratua 2014

Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

nork Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S., Abudayyeh, Omar O., Platt, Randall J., Brigham, Mark D., Sanjana, Neville E., Zhang, Feng
Argitaratua izan da Nat Protoc (2017)

Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d

nork Zhang, Cheng, Konermann, Silvana, Brideau, Nicholas J., Lotfy, Peter, Wu, Xuebing, Novick, Scott J., Strutzenberg, Timothy, Griffin, Patrick R., Hsu, Patrick D., Lyumkis, Dmitry
Argitaratua izan da Cell (2018)

Optical Control of Mammalian Endogenous Transcription and Epigenetic States

nork Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro, Hsu, Patrick D., Heidenreich, Matthias, Cong, Le, Platt, Randall J., Scott, David A., Church, George M., Zhang, Feng
Argitaratua 2013

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

nork Ran, F. Ann, Hsu, Patrick D., Lin, Chie-Yu, Gootenberg, Jonathan S., Konermann, Silvana, Trevino, Alexandro, Scott, David A., Inoue, Azusa, Matoba, Shogo, Zhang, Yi, Zhang, Feng
Argitaratua 2013

Discovery and functional characterization of diverse Class 2 CRISPR-Cas systems

nork Shmakov, Sergey, Abudayyeh, Omar O., Makarova, Kira S., Wolf, Yuri I, Gootenberg, Jonathan S., Semenova, Ekaterina, Minakhin, Leonid, Joung, Julia, Konermann, Silvana, Severinov, Konstantin, Zhang, Feng, Koonin, Eugene V.
Argitaratua izan da Mol Cell (2015)

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

nork Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Abudayyeh, Omar O., Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng
Argitaratua izan da Nature (2014)

CloneSifter: enrichment of rare clones from heterogeneous cell populations

nork Feldman, David, Tsai, FuNien, Garrity, Anthony J., O’Rourke, Ryan, Brenan, Lisa, Ho, Patricia, Gonzalez, Elizabeth, Konermann, Silvana, Johannessen, Cory M., Beroukhim, Rameen, Bandopadhayay, Pratiti, Blainey, Paul C.
Argitaratua izan da BMC Biol (2020)

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

nork Wu, Xuebing, Scott, David A., Kriz, Andrea J., Chiu, Anthony C., Hsu, Patrick D., Dadon, Daniel B., Cheng, Albert W., Trevino, Alexandro E., Konermann, Silvana, Chen, Sidi, Jaenisch, Rudolf, Zhang, Feng, Sharp, Phillip A.
Argitaratua 2014

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

nork Abudayyeh, Omar O., Gootenberg, Jonathan S., Konermann, Silvana, Joung, Julia, Slaymaker, Ian M., Cox, David B.T., Shmakov, Sergey, Makarova, Kira S., Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Regev, Aviv, Lander, Eric S., Koonin, Eugene V., Zhang, Feng
Argitaratua izan da Science (2016)

DNA targeting specificity of RNA-guided Cas9 nucleases

nork Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng
Argitaratua 2013

Genome-scale Activation Screen Identifies a LncRNA Locus that Regulates a Gene Neighborhood

nork Joung, Julia, Engreitz, Jesse M., Konermann, Silvana, Abudayyeh, Omar O., Verdine, Vanessa K., Aguet, Francois, Gootenberg, Jonathan S., Sanjana, Neville E., Wright, Jason B., Fulco, Charles P., Tseng, Yuen-Yi, Yoon, Charles H., Boehm, Jesse S., Lander, Eric S., Zhang, Feng
Argitaratua izan da Nature (2017)

DDIS-13. UNDERSTANDING GLIOBLASTOMA SUSCEPTIBILITY TO TOP2-TARGETING DRUGS FOR PERSONALIZED THERAPY

nork Awah, Chidiebere, Gonzalez-Buendía, Edgar, Zhao, Junfei, Feldstein, Eric, Chen, Li, Mahajan, Aayushi, Warnke, Louisa, Wang, Lu, Park, Cheol, Winter, Jan, Konermann, Silvana, Shilatifard, Ali, James, C David, Rabadan, Raul, Hsu, Patrick, Bansal, Mukesh, Ahmed, Atique, Sonabend, Adam
Argitaratua izan da Neuro Oncol (2018)