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Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d
CRISPR-Cas endonucleases directed against foreign nucleic acids mediate prokaryotic adaptive immunity and have been tailored for broad genetic engineering applications. Type VI-D CRISPR systems contain the smallest known family of single effector Cas enzymes, and their signature Cas13d ribonuclease...
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| Pubblicato in: | Cell |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6179368/ https://ncbi.nlm.nih.gov/pubmed/30241607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.001 |
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