Quantifying On and Off-Target Genome Editing

ανά Hendel, Ayal, Fine, Eli J, Bao, Gang, Porteus, Matthew H
Τόπος έκδοσης Trends Biotechnol (2015)

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

ανά Cradick, Thomas J., Fine, Eli J., Antico, Christopher J., Bao, Gang
Έκδοση 2013

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

ανά Lee, Ciaran M, Cradick, Thomas J, Fine, Eli J, Bao, Gang
Τόπος έκδοσης Mol Ther (2016)

Nanomedicine: Tiny Particles and Machines Give Huge Gains

ανά Tong, Sheng, Fine, Eli J., Lin, Yanni, Cradick, Thomas J., Bao, Gang
Έκδοση 2013

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

ανά Fine, Eli J., Cradick, Thomas J., Zhao, Charles L., Lin, Yanni, Bao, Gang
Έκδοση 2014

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

ανά Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang
Τόπος έκδοσης Mol Ther Nucleic Acids (2014)

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

ανά Mussolino, Claudio, Alzubi, Jamal, Fine, Eli J., Morbitzer, Robert, Cradick, Thomas J., Lahaye, Thomas, Bao, Gang, Cathomen, Toni
Έκδοση 2014

Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes

ανά Fine, Eli J., Appleton, Caleb M., White, Douglas E., Brown, Matthew T., Deshmukh, Harshavardhan, Kemp, Melissa L., Bao, Gang
Τόπος έκδοσης Sci Rep (2015)

Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing

ανά Hendel, Ayal, Kildebeck, Eric J, Fine, Eli J, Clark, Joseph, Punjya, Niraj, Sebastiano, Vittorio, Bao, Gang, Porteus, Matthew H
Έκδοση 2014

Preclinical Development of a Hematopoietic Stem and Progenitor Cell Bioengineered Factor VIII Lentiviral Vector Gene Therapy for Hemophilia A

ανά Doering, Christopher B., Denning, Gabriela, Shields, Jordan E., Fine, Eli J., Parker, Ernest T., Srivastava, Alok, Lollar, Pete, Spencer, H. Trent
Τόπος έκδοσης Hum Gene Ther (2018)

SAPTA: a new design tool for improving TALE nuclease activity

ανά Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Έκδοση 2014

DNA targeting specificity of RNA-guided Cas9 nucleases

ανά Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng
Έκδοση 2013

CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

ανά Vilarino, Marcela, Rashid, Sheikh Tamir, Suchy, Fabian Patrik, McNabb, Bret Roberts, van der Meulen, Talitha, Fine, Eli J., Ahsan, Syed Daniyal, Mursaliyev, Nurlybek, Sebastiano, Vittorio, Diab, Santiago Sain, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo J.
Τόπος έκδοσης Sci Rep (2017)

Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

ανά Vilarino, Marcela, Rashid, Sheikh Tamir, Suchy, Fabian Patrik, McNabb, Bret Roberts, van der Meulen, Talitha, Fine, Eli J., Ahsan, Syed Daniyal, Mursaliyev, Nurlybek, Sebastiano, Vittorio, Diab, Santiago Sain, Huising, Mark O., Nakauchi, Hiromitsu, Ross, Pablo J.
Τόπος έκδοσης Sci Rep (2020)

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

ανά Suzuki, Shingo, Sargent, R Geoffrey, Illek, Beate, Fischer, Horst, Esmaeili-Shandiz, Alaleh, Yezzi, Michael J, Lee, Albert, Yang, Yanu, Kim, Soya, Renz, Peter, Qi, Zhongxia, Yu, Jingwei, Muench, Marcus O, Beyer, Ashley I, Guimarães, Alessander O, Ye, Lin, Chang, Judy, Fine, Eli J, Cradick, Thomas J, Bao, Gang, Rahdar, Meghdad, Porteus, Matthew H, Shuto, Tsuyoshi, Kai, Hirofumi, Kan, Yuet W, Gruenert, Dieter C
Τόπος έκδοσης Mol Ther Nucleic Acids (2016)