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Quantifying On and Off-Target Genome Editing

Genome editing with engineered nucleases is a rapidly growing field, thanks to transformative technologies that allow researchers to precisely alter genomes for numerous applications, including basic research, biotechnology, and human gene therapy. While the capability to make precise and controlled...

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Bibliographic Details
Published in:Trends Biotechnol
Main Authors: Hendel, Ayal, Fine, Eli J, Bao, Gang, Porteus, Matthew H
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308725/
https://ncbi.nlm.nih.gov/pubmed/25595557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2014.12.001
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