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Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing
Targeted genome editing with engineered nucleases has transformed the ability to introduce precise sequence modifications at almost any site within the genome. A major obstacle to probing the efficiency and consequences of genome editing is that no existing method enables the frequency of different...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015468/ https://ncbi.nlm.nih.gov/pubmed/24685129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.040 |
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