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Preclinical Development of a Hematopoietic Stem and Progenitor Cell Bioengineered Factor VIII Lentiviral Vector Gene Therapy for Hemophilia A
Genetically modified, autologous hematopoietic stem and progenitor cells (HSPCs) represent a new class of genetic medicine. Following this therapeutic paradigm, we are developing a product candidate, designated CD68-ET3-LV CD34(+), for the treatment of the severe bleeding disorder, hemophilia A. The...
Kaydedildi:
| Yayımlandı: | Hum Gene Ther |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Mary Ann Liebert, Inc., publishers
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196756/ https://ncbi.nlm.nih.gov/pubmed/30160169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.137 |
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