Carregant...

Comparison of Factor VIII Transgenes Bioengineered for Improved Expression in Gene Therapy of Hemophilia A

Successful gene therapy of hemophilia A depends on the sustained expression of therapeutic levels of factor VIII (fVIII). Because of mRNA instability, interactions with resident endoplasmic reticulum (ER) chaperones, and the requirement for carbohydrate-facilitated transport from the ER to the Golgi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Dooriss, Kerry L., Denning, Gabriela, Gangadharan, Bagirath, Javazon, Elisabeth H., McCarty, David A., Spencer, H. Trent, Doering, Christopher B.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828624/
https://ncbi.nlm.nih.gov/pubmed/19222367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.150
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!