SAPTA: a new design tool for improving TALE nuclease activity

Transcription activator-like effector nucleases (TALENs) have become a powerful tool for genome editing due to the simple code linking the amino acid sequences of their DNA-binding domains to TALEN nucleotide targets. While the initial TALEN-design guidelines are very useful, user-friendly tools def...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973288/
https://ncbi.nlm.nih.gov/pubmed/24442582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1363
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