In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

Dysfunctional endothelium contributes to more disease than any other tissue in the body. Small interfering RNAs (siRNAs) have the potential to help study and treat endothelial cells in vivo by durably silencing multiple genes simultaneously, but efficient siRNA delivery has so far remained challengi...

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Bibliografische gegevens
Hoofdauteurs: Dahlman, James E., Barnes, Carmen, Khan, Omar, Thiriot, Aude, Jhunjunwala, Siddharth, Shaw, Taylor E., Xing, Yiping, Sager, Hendrik B., Sahay, Gaurav, Speciner, Lauren, Bader, Andrew, Bogorad, Roman L., Yin, Hao, Racie, Tim, Dong, Yizhou, Jiang, Shan, Seedorf, Danielle, Dave, Apeksha, Sandu, Kamaljeet S., Webber, Matthew J., Novobrantseva, Tatiana, Ruda, Vera M., Lytton-Jean, Abigail K.R., Levins, Christopher G., Kalish, Brian, Mudge, Dayna K., Perez, Mario, Abezgauz, Ludmila, Dutta, Partha, Smith, Lynelle, Charisse, Klaus, Kieran, Mark W., Fitzgerald, Kevin, Nahrendorf, Matthias, Danino, Dganit, Tuder, Rubin M., von Andrian, Ulrich H., Akinc, Akin, Schroeder, Avi, Panigrahy, Dipak, Kotelianski, Victor, Langer, Robert, Anderson, Daniel G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207430/
https://ncbi.nlm.nih.gov/pubmed/24813696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2014.84
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