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The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo
Argonaute 2 (Ago2) is the only mammalian Ago protein capable of mRNA cleavage. It has been reported that the activity of the short interfering RNA targeting coding sequence (CDS), but not 3′ untranslated region (3′UTR) of an mRNA, is solely dependent on Ago2 in vitro. These studies utilized extremel...
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| Main Authors: | , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
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Public Library of Science
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081796/ https://ncbi.nlm.nih.gov/pubmed/24992693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101749 |
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