The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo

Argonaute 2 (Ago2) is the only mammalian Ago protein capable of mRNA cleavage. It has been reported that the activity of the short interfering RNA targeting coding sequence (CDS), but not 3′ untranslated region (3′UTR) of an mRNA, is solely dependent on Ago2 in vitro. These studies utilized extremel...

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Xehetasun bibliografikoak
Egile Nagusiak: Ruda, Vera M., Chandwani, Rohit, Sehgal, Alfica, Bogorad, Roman L., Akinc, Akin, Charisse, Klaus, Tarakhovsky, Alexander, Novobrantseva, Tatiana I., Koteliansky, Victor
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081796/
https://ncbi.nlm.nih.gov/pubmed/24992693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101749
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