Quantitative functions of Argonaute proteins in mammalian development

Argonaute proteins (Ago1–4) are essential components of the microRNA-induced silencing complex and play important roles in both microRNA biogenesis and function. Although Ago2 is the only one with the slicer activity, it is not clear whether the slicer activity is a universally critical determinant...

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Detalhes bibliográficos
Main Authors: Wang, Dongmei, Zhang, Zhaojie, O'Loughlin, Evan, Lee, Thomas, Houel, Stephane, O'Carroll, Dónal, Tarakhovsky, Alexander, Ahn, Natalie G., Yi, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323880/
https://ncbi.nlm.nih.gov/pubmed/22474261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.182758.111
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