Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

Por Zatsepin, Timofei S, Kotelevtsev, Yuri V, Koteliansky, Victor
Publicado no Int J Nanomedicine (2016)

In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor: A potential new therapy for hepatic fibrosis

Por George, Jacob, Roulot, Dominique, Koteliansky, Victor E., Bissell, D. Montgomery
Publicado em 1999

Cell and Molecular Regulation of Endothelin-1 Production during Hepatic Wound Healing

Por Shao, Rong, Shi, Zengdun, Gotwals, Philip J., Koteliansky, Victor E., George, Jacob, Rockey, Don C.
Publicado em 2003

The α(1)β(1) and α(2)β(1) Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis

Por Senger, Donald R., Perruzzi, Carole A., Streit, Michael, Koteliansky, Victor E., de Fougerolles, Antonin R., Detmar, Michael
Publicado em 2002

Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

Por Bogorad, Roman L, Yin, Hao, Zeigerer, Anja, Nonaka, Hidenori, Ruda, Vera, Zerial, Marino, Anderson, Daniel G, Koteliansky, Victor
Publicado em 2014

Sonic hedgehog restricts adhesion and migration of neural crest cells independently of the Patched- Smoothened-Gli signaling pathway

Por Testaz, Sandrine, Jarov, Artem, Williams, Kevin P., Ling, Leona E., Koteliansky, Victor E., Fournier-Thibault, Claire, Duband, Jean-Loup
Publicado em 2001

Transforming Growth Factor-β Initiates Wound Repair in Rat Liver through Induction of the EIIIA-Fibronectin Splice Isoform

Por George, Jacob, Wang, Shao-Shean, Sevcsik, Ann-Marie, Sanicola, Michele, Cate, Richard L., Koteliansky, Victor E., Bissell, D. Montgomery
Publicado em 2000

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

Por Lutgens, Esther, Cleutjens, Kitty B. J. M., Heeneman, Sylvia, Koteliansky, Victor E., Burkly, Linda C., Daemen, Mat J. A. P.
Publicado em 2000

α5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation

Por Klein, Sharon, de Fougerolles, Antonin R., Blaikie, Pamela, Khan, Leila, Pepe, Angela, Green, Cynthia D., Koteliansky, Victor, Giancotti, Filippo G.
Publicado em 2002

Muscle β1D Integrin Reinforces the Cytoskeleton–Matrix Link: Modulation of Integrin Adhesive Function by Alternative Splicing

Por Belkin, Alexey M., Retta, S. Francesco, Pletjushkina, Olga Y., Balzac, Fiorella, Silengo, Lorenzo, Fassler, Reinhard, Koteliansky, Victor E., Burridge, Keith, Tarone, Guido
Publicado em 1997

The Roles of Individual Mammalian Argonautes in RNA Interference In Vivo

Por Ruda, Vera M., Chandwani, Rohit, Sehgal, Alfica, Bogorad, Roman L., Akinc, Akin, Charisse, Klaus, Tarakhovsky, Alexander, Novobrantseva, Tatiana I., Koteliansky, Victor
Publicado em 2014

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

Por Moon, Young-Ah, Liang, Guosheng, Xie, Xuefen, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Brown, Michael S., Goldstein, Joseph L., Horton, Jay D.
Publicado em 2012

Attenuated liver fibrosis in the absence of B cells

Por Novobrantseva, Tatiana I., Majeau, Gerard R., Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, Shlomchik, Mark J., Koteliansky, Victor, Hochman, Paula S., Ibraghimov, Alexander
Publicado em 2005

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

Por Hur, Kyu Yeon, So, Jae-Seon, Ruda, Vera, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Iwawaki, Takao, Glimcher, Laurie H., Lee, Ann-Hwee
Publicado em 2012

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

Por Yin, Hao, Xue, Wen, Chen, Sidi, Bogorad, Roman L, Benedetti, Eric, Grompe, Markus, Koteliansky, Victor, Sharp, Phillip A, Jacks, Tyler, Anderson, Daniel G
Publicado em 2014

Treatment of erythropoietin deficiency in mice with systemically administered siRNA

Por Querbes, William, Bogorad, Roman L., Moslehi, Javid, Wong, Jamie, Chan, Amy Y., Bulgakova, Elena, Kuchimanchi, Satya, Akinc, Akin, Fitzgerald, Kevin, Koteliansky, Victor, Kaelin, William G.
Publicado em 2012

Collagen-binding integrin α(1)β(1) regulates intestinal inflammation in experimental colitis

Por Krieglstein, Christian F., Cerwinka, Wolfgang H., Sprague, Andrew G., Laroux, F. Stephen, Grisham, Matthew B., Koteliansky, Victor E., Senninger, Norbert, Granger, D. Neil, de Fougerolles, Antonin R.
Publicado em 2002

Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis

Por de Fougerolles, Antonin R., Sprague, Andrew G., Nickerson-Nutter, Cheryl L., Chi-Rosso, Gloria, Rennert, Paul D., Gardner, Humphrey, Gotwals, Philip J., Lobb, Roy R., Koteliansky, Victor E.
Publicado em 2000

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice

Por So, Jae-Seon, Hur, Kyu Yeon, Tarrio, Margarite, Ruda, Vera, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Lichtman, Andrew H., Iwawaki, Takao, Glimcher, Laurie H., Lee, Ann-Hwee
Publicado em 2012

Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β(1)

Por Lee, Chun Geun, Homer, Robert J., Zhu, Zhou, Lanone, Sophie, Wang, Xiaoman, Koteliansky, Victor, Shipley, J. Michael, Gotwals, Philip, Noble, Paul, Chen, Qingsheng, Senior, Robert M., Elias, Jack A.
Publicado em 2001