Treatment of erythropoietin deficiency in mice with systemically administered siRNA

Anemia linked to a relative deficiency of renal erythropoietin production is a significant cause of morbidity and medical expenditures in the developed world. Recombinant erythropoietin is expensive and has been linked to excess cardiovascular events. Moreover, some patients become refractory to ery...

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Bibliographische Detailangaben
Hauptverfasser: Querbes, William, Bogorad, Roman L., Moslehi, Javid, Wong, Jamie, Chan, Amy Y., Bulgakova, Elena, Kuchimanchi, Satya, Akinc, Akin, Fitzgerald, Kevin, Koteliansky, Victor, Kaelin, William G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Red Cells, Iron, and Erythropoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433093/
https://ncbi.nlm.nih.gov/pubmed/22611156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-423715
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