Infection of Vero Cells by BK Virus Is Dependent on Caveolae

per Eash, Sylvia, Querbes, William, Atwood, Walter J.
Publicat 2004

Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression

per Burgess, Alison, Huang, Yuexi, Querbes, William, Sah, Dinah W., Hynynen, Kullervo
Publicat 2012

Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

per Whitehead, Kathryn A, Sahay, Gaurav, Li, George Z, Love, Kevin T, Alabi, Christopher A, Ma, Minglin, Zurenko, Christopher, Querbes, William, Langer, Robert S, Anderson, Daniel G
Publicat 2011

Treatment of erythropoietin deficiency in mice with systemically administered siRNA

per Querbes, William, Bogorad, Roman L., Moslehi, Javid, Wong, Jamie, Chan, Amy Y., Bulgakova, Elena, Kuchimanchi, Satya, Akinc, Akin, Fitzgerald, Kevin, Koteliansky, Victor, Kaelin, William G.
Publicat 2012

RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice

per Yasuda, Makiko, Gan, Lin, Chen, Brenden, Kadirvel, Senkottuvelan, Yu, Chunli, Phillips, John D., New, Maria I., Liebow, Abigail, Fitzgerald, Kevin, Querbes, William, Desnick, Robert J.
Publicat 2014

Metabolism of (13)C(5)-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrog...

per Li, Xingsheng, Knight, John, Fargue, Sonia, Buchalski, Brianna, Guan, Zhengrong, Inscho, Edward W, Liebow, Abigail, Fitzgerald, Kevin, Querbes, William, Lowther, W. Todd, Holmes, Ross P.
Publicat a Biochim Biophys Acta (2015)

Patient Perspective on Acute Intermittent Porphyria with Frequent Attacks: A Disease with Intermittent and Chronic Manifestations

per Simon, Amy, Pompilus, Farrah, Querbes, William, Wei, Alex, Strzok, Sara, Penz, Craig, Howe, Desiree Lyon, Hungate, Jessica R., Kim, Jae B., Agarwal, Sonalee, Marquis, Patrick
Publicat a Patient (2018)

An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria

per Liebow, Abigail, Li, Xingsheng, Racie, Timothy, Hettinger, Julia, Bettencourt, Brian R., Najafian, Nader, Haslett, Patrick, Fitzgerald, Kevin, Holmes, Ross P., Erbe, David, Querbes, William, Knight, John
Publicat a J Am Soc Nephrol (2017)

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

per Sahay, Gaurav, Querbes, William, Alabi, Christopher, Eltoukhy, Ahmed, Sarkar, Sovan, Zurenko, Christopher, Karagiannis, Emannouil, Love, Kevin, Chen, Delai, Zoncu, Roberto, Buganim, Yosef, Schroeder, Avi, Langer, Robert, Anderson, Daniel G.
Publicat 2013

Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins

per Xu, Yu-Xin, Redon, Valeska, Yu, Haojie, Querbes, William, Pirruccello, James, Liebow, Abigail, Deik, Amy, Trindade, Kevin, Wang, Xiao, Musunuru, Kiran, Clish, Clary B., Cowan, Chad, Fizgerald, Kevin, Rader, Daniel, Kathiresan, Sekar
Publicat a Atherosclerosis (2017)

Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification

per Chan, Amy, Liebow, Abigail, Yasuda, Makiko, Gan, Lin, Racie, Tim, Maier, Martin, Kuchimanchi, Satya, Foster, Don, Milstein, Stuart, Charisse, Klaus, Sehgal, Alfica, Manoharan, Muthiah, Meyers, Rachel, Fitzgerald, Kevin, Simon, Amy, Desnick, Robert J, Querbes, William
Publicat a Mol Ther Nucleic Acids (2015)

Identification of siRNA delivery enhancers by a chemical library screen

per Gilleron, Jerome, Paramasivam, Prasath, Zeigerer, Anja, Querbes, William, Marsico, Giovanni, Andree, Cordula, Seifert, Sarah, Amaya, Pablo, Stöter, Martin, Koteliansky, Victor, Waldmann, Herbert, Fitzgerald, Kevin, Kalaidzidis, Yannis, Akinc, Akin, Maier, Martin A., Manoharan, Muthiah, Bickle, Marc, Zerial, Marino
Publicat a Nucleic Acids Res (2015)

Modular ‘Click-in-Emulsion’ Bone-Targeted Nanogels

per Heller, Daniel A., Levi, Yair, Pelet, Jeisa M., Doloff, Joshua C., Wallas, Jasmine, Pratt, George W., Jiang, Shan, Sahay, Gaurav, Schroeder, Avi, Schroeder, Josh E., Chyan, Yieu, Zurenko, Christopher, Querbes, William, Manzano, Miguel, Kohane, Daniel S., Langer, Robert, Anderson, Daniel G.
Publicat 2012

Molecularly Self-Assembled Nucleic Acid Nanoparticles for Targeted In Vivo siRNA Delivery

per Lee, Hyukjin, Lytton-Jean, Abigail K. R., Chen, Yi, Love, Kevin T., Park, Angela I., Karagiannis, Emmanouil D., Sehgal, Alfica, Querbes, William, Zurenko, Christopher S., Jayaraman, Muthusamy, Peng, Chang G., Charisse, Klaus, Borodovsky, Anna, Manoharan, Muthiah, Donahoe, Jessica S., Truelove, Jessica, Nahrendorf, Matthias, Langer, Robert, Anderson, Daniel G.
Publicat 2012

Lipid-like materials for low-dose, in vivo gene silencing

per Love, Kevin T., Mahon, Kerry P., Levins, Christopher G., Whitehead, Kathryn A., Querbes, William, Dorkin, J. Robert, Qin, June, Cantley, William, Qin, Liu Liang, Racie, Timothy, Frank-Kamenetsky, Maria, Yip, Ka Ning, Alvarez, Rene, Sah, Dinah W. Y., de Fougerolles, Antonin, Fitzgerald, Kevin, Koteliansky, Victor, Akinc, Akin, Langer, Robert, Anderson, Daniel G.
Publicat 2010

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

per Siegwart, Daniel J., Whitehead, Kathryn A., Nuhn, Lutz, Sahay, Gaurav, Cheng, Hao, Jiang, Shan, Ma, Minglin, Lytton-Jean, Abigail, Vegas, Arturo, Fenton, Patrick, Levins, Christopher G., Love, Kevin T., Lee, Haeshin, Cortez, Christina, Collins, Sean P., Li, Ying Fei, Jang, Janice, Querbes, William, Zurenko, Christopher, Novobrantseva, Tatiana, Langer, Robert, Anderson, Daniel G.
Publicat 2011

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

per Akinc, Akin, Querbes, William, De, Soma, Qin, June, Frank-Kamenetsky, Maria, Jayaprakash, K. Narayanannair, Jayaraman, Muthusamy, Rajeev, Kallanthottathil G, Cantley, William L, Dorkin, J Robert, Butler, James S, Qin, LiuLiang, Racie, Timothy, Sprague, Andrew, Fava, Eugenio, Zeigerer, Anja, Hope, Michael J, Zerial, Marino, Sah, Dinah WY, Fitzgerald, Kevin, Tracy, Mark A, Manoharan, Muthiah, Koteliansky, Victor, Fougerolles, Antonin de, Maier, Martin A
Publicat 2010

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

per Maier, Martin A, Jayaraman, Muthusamy, Matsuda, Shigeo, Liu, Ju, Barros, Scott, Querbes, William, Tam, Ying K, Ansell, Steven M, Kumar, Varun, Qin, June, Zhang, Xuemei, Wang, Qianfan, Panesar, Sue, Hutabarat, Renta, Carioto, Mary, Hettinger, Julia, Kandasamy, Pachamuthu, Butler, David, Rajeev, Kallanthottathil G, Pang, Bo, Charisse, Klaus, Fitzgerald, Kevin, Mui, Barbara L, Du, Xinyao, Cullis, Pieter, Madden, Thomas D, Hope, Michael J, Manoharan, Muthiah, Akinc, Akin
Publicat 2013

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

per Novobrantseva, Tatiana I, Borodovsky, Anna, Wong, Jamie, Klebanov, Boris, Zafari, Mohammad, Yucius, Kristina, Querbes, William, Ge, Pei, Ruda, Vera M, Milstein, Stuart, Speciner, Lauren, Duncan, Rick, Barros, Scott, Basha, Genc, Cullis, Pieter, Akinc, Akin, Donahoe, Jessica S, Narayanannair Jayaprakash, K, Jayaraman, Muthusamy, Bogorad, Roman L, Love, Kevin, Whitehead, Katie, Levins, Chris, Manoharan, Muthiah, Swirski, Filip K, Weissleder, Ralph, Langer, Robert, Anderson, Daniel G, de Fougerolles, Antonin, Nahrendorf, Matthias, Koteliansky, Victor
Publicat 2012

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

per Dong, Yizhou, Love, Kevin T., Dorkin, J. Robert, Sirirungruang, Sasilada, Zhang, Yunlong, Chen, Delai, Bogorad, Roman L., Yin, Hao, Chen, Yi, Vegas, Arturo J., Alabi, Christopher A., Sahay, Gaurav, Olejnik, Karsten T., Wang, Weiheng, Schroeder, Avi, Lytton-Jean, Abigail K. R., Siegwart, Daniel J., Akinc, Akin, Barnes, Carmen, Barros, Scott A., Carioto, Mary, Fitzgerald, Kevin, Hettinger, Julia, Kumar, Varun, Novobrantseva, Tatiana I., Qin, June, Querbes, William, Koteliansky, Victor, Langer, Robert, Anderson, Daniel G.
Publicat 2014