ATRP in the design of functional materials for biomedical applications

Por Siegwart, Daniel J., Oh, Jung Kwon, Matyjaszewski, Krzysztof
Publicado em 2011

Strategies, Design, and Chemistry in siRNA Delivery Systems

Por Dong, Yizhou, Siegwart, Daniel J., Anderson, Daniel G.
Publicado no Adv Drug Deliv Rev (2019)

Automated ARGET ATRP Accelerates Catalyst Optimization for the Synthesis of Thiol-Functionalized Polymers

Por Siegwart, Daniel J., Leiendecker, Matthias, Langer, Robert, Anderson, Daniel G.
Publicado em 2012

Degradable Redox-Responsive Disulfide-Based Nanogel Drug Carriers via Dithiol Oxidation Polymerization

Por Elkassih, Sussana A., Kos, Petra, Xiong, Hu, Siegwart, Daniel J.
Publicado no Biomater Sci (2019)

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing

Por Wei, Tuo, Cheng, Qiang, Min, Yi-Li, Olson, Eric N., Siegwart, Daniel J.
Publicado no Nat Commun (2020)

Selective ORgan Targeting (SORT) nanoparticles for tissue specific mRNA delivery and CRISPR/Cas gene editing

Por Cheng, Qiang, Wei, Tuo, Farbiak, Lukas, Johnson, Lindsay T., Dilliard, Sean A., Siegwart, Daniel J.
Publicado no Nat Nanotechnol (2020)

Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for in Vivo CRISPR/Cas-Based Genome Editing

Por Wei, Tuo, Cheng, Qiang, Farbiak, Lukas, Anderson, Daniel G., Langer, Robert, Siegwart, Daniel J.
Publicado no ACS Nano (2020)

Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity

Por Eltoukhy, Ahmed A., Siegwart, Daniel J., Alabi, Christopher A., Rajan, Jay S., Langer, Robert, Anderson, Daniel G.
Publicado em 2012

Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization

Por Bencherif, Sidi A., Siegwart, Daniel J., Srinivasan, Abiraman, Horkay, Ferenc, Hollinger, Jeffrey O., Washburn, Newell R., Matyjaszewski, Krzysztof
Publicado em 2009

Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

Por Chen, Peiwen, Zuo, Hao, Xiong, Hu, Kolar, Matthew J., Chu, Qian, Saghatelian, Alan, Siegwart, Daniel J., Wan, Yihong
Publicado no Proc Natl Acad Sci U S A (2017)

Non-viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co-delivery of Cas9 mRNA and sgRNA

Por Miller, Jason B., Zhang, Shuyuan, Kos, Petra, Xiong, Hu, Zhou, Kejin, Perelman, Sofya S., Zhu, Hao, Siegwart, Daniel J.
Publicado no Angew Chem Int Ed Engl (2016)

HDAC Inhibitor Conjugated Polymeric Prodrug Micelles for Doxorubicin Delivery

Por Senevirathne, Suchithra A., Washington, Katherine E., Miller, Jason B., Biewer, Michael C., Oupicky, David, Siegwart, Daniel J., Stefan, Mihaela C.
Publicado no J Mater Chem B Mater Biol Med (2017)

Development of Cationic Polymer Coatings to Regulate Foreign Body Responses

Por Ma, Minglin, Liu, Wendy F., Hill, Paulina S., Bratlie, Kaitlin M., Siegwart, Daniel J., Chin, Justin, Park, Miri, Guerreiro, Joao, Anderson, Daniel G.
Publicado em 2011

One-pot Synthesis of Functional Poly(amino ester sulfide)s and Utility in Delivering pDNA and siRNA

Por Yan, Yunfeng, Xue, Lian, Miller, Jason B., Zhou, Kejin, Kos, Petra, Elkassih, Sussana, Liu, Li, Nagai, Atsushi, Xiong, Hu, Siegwart, Daniel J.
Publicado no Polymer (Guildf) (2015)

Cellular uptake of functional nanogels prepared by inverse miniemulsion ATRP with encapsulated proteins, carbohydrates, and gold nanoparticles

Por Siegwart, Daniel J., Srinivasan, Abiraman, Bencherif, Sidi A., Karunanidhi, Anuradha, Oh, Jung Kwon, Vaidya, Swaroopa, Jin, Rongchao, Hollinger, Jeffrey O., Matyjaszewski, Krzysztof
Publicado no Biomacromolecules (2009)

A Novel Family of Biodegradable Poly(ester amide) Elastomers

Por Cheng, Hao, Hill, Paulina S., Siegwart, Daniel J., Vacanti, Nathaniel, Lytton-Jean, Abigail K. R., Cho, Seung-Woo, Ye, Anne, Langer, Robert, Anderson, Daniel G.
Publicado em 2011

Nanoparticulate Cellular Patches for Cell-Mediated Tumoritropic Delivery

Por Cheng, Hao, Kastrup, Christian J., Ramanathan, Renuka, Siegwart, Daniel J., Ma, Minglin, Bogatyrev, Said R., Xu, Qiaobing, Whitehead, Kathryn A., Langer, Robert, Anderson, Daniel G.
Publicado em 2010

Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model

Por Zhou, Kejin, Nguyen, Liem H., Miller, Jason B., Yan, Yunfeng, Kos, Petra, Xiong, Hu, Li, Lin, Hao, Jing, Minnig, Jonathan T., Zhu, Hao, Siegwart, Daniel J.
Publicado no Proc Natl Acad Sci U S A (2016)

The Polyploid State Plays a Tumor-Suppressive Role in the Liver

Por Zhang, Shuyuan, Zhou, Kejin, Luo, Xin, Li, Lin, Tu, Ho-Chou, Sehgal, Alfica, Nguyen, Liem H., Zhang, Yu, Gopal, Purva, Tarlow, Branden D., Siegwart, Daniel J., Zhu, Hao
Publicado no Dev Cell (2018)

An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate

Por Pritchard, Christopher D., O’Shea, Timothy M., Siegwart, Daniel J., Calo, Eliezer, Anderson, Daniel G., Reynolds, Francis M., Thomas, John A., Slotkin, Jonathan R., Woodard, Eric J., Langer, Robert
Publicado em 2010