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Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity
Amine end-modified poly(ß-amino ester)s (PBAEs) have generated interest as efficient, biodegradable polymeric carriers for plasmid DNA (pDNA). For cationic, non-degradable polymers, such as polyethylenimine (PEI), the polymer molecular weight (MW) and molecular weight distribution (MWD) significantl...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326358/ https://ncbi.nlm.nih.gov/pubmed/22341939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.046 |
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