Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity

Amine end-modified poly(ß-amino ester)s (PBAEs) have generated interest as efficient, biodegradable polymeric carriers for plasmid DNA (pDNA). For cationic, non-degradable polymers, such as polyethylenimine (PEI), the polymer molecular weight (MW) and molecular weight distribution (MWD) significantl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Eltoukhy, Ahmed A., Siegwart, Daniel J., Alabi, Christopher A., Rajan, Jay S., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326358/
https://ncbi.nlm.nih.gov/pubmed/22341939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.046
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker