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Gold, Poly(β-amino ester) Nanoparticles for Small Interfering RNA Delivery

The safe and effective delivery of RNA therapeutics remains the major barrier to their broad clinical application. Here we develop a new nanoparticulate delivery system based on inorganic particles and biodegradable polycations. First, gold nanoparticles were modified with the hydrophilic polymer po...

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Detalhes bibliográficos
Main Authors: Lee, Jae-Seung, Green, Jordan J., Love, Kevin T., Sunshine, Joel, Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728206/
https://ncbi.nlm.nih.gov/pubmed/19422265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl9009793
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