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Bioreducible poly(beta-amino ester)s for intracellular delivery of siRNA

RNA interference (RNAi) is a powerful tool to target and knockdown gene expression in a sequence-specific manner. RNAi can be achieved by the intracellular introduction of siRNA, however, intracellular siRNA delivery remains a challenging obstacle. Herein we describe the use of bioreducible nanopart...

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Publicado en:Methods Mol Biol
Main Authors: Kozielski, Kristen L., Green, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745093/
https://ncbi.nlm.nih.gov/pubmed/26472444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3112-5_8
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