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A bioreducible linear poly(β-amino ester) for siRNA delivery

Described here is the synthesis and characterization of a novel, bioreducible linear poly(β-amino ester) designed to condense siRNA into nanoparticles and efficiently release it upon entering the cytoplasm. Delivery of siRNA using this polymer achieved near-complete knockdown of a fluorescent marker...

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Bibliografski detalji
Glavni autori: Kozielski, Kristen L., Tzeng, Stephany Y., Green, Jordan J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894248/
https://ncbi.nlm.nih.gov/pubmed/23646347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc40718g
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