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VEGF siRNA Delivery System Using Arginine-Grafted Bioreducible Poly(disulfide amine)

Small interfering RNAs (siRNAs) are able to silence their target genes when they are successfully delivered intact into the cytoplasm. Delivery systems that enhance siRNA localization to the cytoplasm can facilitate gene silencing by siRNA therapeutics. We describe an arginine-conjugated poly(cystam...

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Detalhes bibliográficos
Main Authors: Kim, Sun Hwa, Jeong, Ji Hoon, Kim, Tae-il, Kim, Sung Wan, Bull, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754713/
https://ncbi.nlm.nih.gov/pubmed/19055368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800161e
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