Non-Viral Gene Delivery Nanoparticles Based on Poly(β-amino esters) for Treatment of Glioblastoma

Glioblastoma (GB) is currently characterized by low survival rates and therapies with insufficient efficacy. Here, we describe biodegradable polymers that can deliver genes to primary GB cells as well as GB tumor stem cells in vitro with low non-specific toxicity and transfection efficiencies of up...

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Hauptverfasser: Tzeng, Stephany T., Guerrero-Cázares, Hugo, Martinez, Elliott E., Sunshine, Joel C., Quiñones-Hinojosa, Alfredo, Green, Jordan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118545/
https://ncbi.nlm.nih.gov/pubmed/21536325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.04.016
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