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Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for in Vivo CRISPR/Cas-Based Genome Editing

CRISPR/Cas9-based genome editing has quickly emerged as a powerful breakthrough technology for use in diverse settings across biomedical research and therapeutic development. Recent efforts toward understanding gene modification methods in vitro have led to substantial improvements in ex vivo genome...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Wei, Tuo, Cheng, Qiang, Farbiak, Lukas, Anderson, Daniel G., Langer, Robert, Siegwart, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996671/
https://ncbi.nlm.nih.gov/pubmed/32697075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c04707
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