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In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges

The successful use of CRISPR/Cas9 based gene editing for therapeutics requires efficient in vivo delivery of the CRISPR components. There are, however, major challenges on the delivery front. In this Topical Review, we will highlight recent developments in CRISPR delivery, and we will present hurdle...

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Dettagli Bibliografici
Pubblicato in:Bioconjug Chem
Autori principali: Mout, Rubul, Ray, Moumita, Lee, Yi-Wei, Scaletti, Federica, Rotello, Vincent M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846329/
https://ncbi.nlm.nih.gov/pubmed/28263568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00057
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